Aluminium hydroxide is a common ingredient in antacids and some kidney medicines. It neutralizes stomach acid fast and can bind phosphate in people with chronic kidney disease (CKD). If you’ve picked up an antacid from the pharmacy or been told to control phosphate levels, this is likely one of the active ingredients.
As an antacid, aluminium hydroxide reacts with stomach acid to form water and neutral salts. That gives quick relief from heartburn, indigestion, and sour stomach. In CKD, aluminium binds dietary phosphate in the gut so less phosphate is absorbed — that helps keep blood phosphate from rising.
Available forms include chewable tablets and liquid suspensions. Some over-the-counter products mix aluminium hydroxide with magnesium hydroxide to reduce constipation (aluminium causes constipation; magnesium causes loose stools).
Short-term use for heartburn is usually safe for most people. Common side effects are constipation and mild stomach upset. The bigger concern is long-term or high-dose use, especially in people with poor kidney function. If your kidneys don’t clear aluminium well, the metal can build up and cause bone pain, muscle weakness, or even mental changes (confusion, memory problems).
Aluminium also binds several medicines and lowers their absorption. That includes tetracycline and fluoroquinolone antibiotics, levothyroxine, and some iron supplements. To avoid this, take aluminium-containing antacids at least 2 hours before or 2–4 hours after these drugs.
For people on dialysis or with chronic kidney disease, doctors usually prefer non-aluminium phosphate binders because of the risk of aluminium accumulation. If your doctor prescribes aluminium hydroxide for phosphate control, expect regular blood tests to check phosphate, aluminum levels, and bone health.
Pregnant or breastfeeding? Ask your clinician. Short-term antacid use is often allowed, but dosing and safety depend on your situation. For babies and children, follow exact pediatric dosing — don’t guess.
Practical tips: use the smallest effective dose for the shortest time; avoid combining multiple antacid products unless advised; space other oral meds around aluminium to prevent interactions; and tell your provider if you have kidney disease, recurring heartburn, or new bone or brain symptoms while using aluminium products.
If heartburn or reflux keeps coming back despite antacids, or if you notice persistent constipation, dark stools, bone pain, or confusion, see a doctor. There are safer long-term options for acid control and phosphate management that your clinician can recommend based on your health and blood tests.